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Fri, Jan 12



Integrative Approach Targeting the Vagus Nerve and the Neuroendocrine-Immune System (NEIS). 2d Ed. Part 2.

Part 2 (3-day course) will review other cranial nerves in relation to the vagus nerve, brain inflammation and neurotoxicity, key neurohormones in neuromodulation, HRV analysis, manual treatment and bioelectronic medicine.

Integrative Approach Targeting the Vagus Nerve and the Neuroendocrine-Immune System (NEIS). 2d Ed. Part 2.
Integrative Approach Targeting the Vagus Nerve and the Neuroendocrine-Immune System (NEIS). 2d Ed. Part 2.

Time & Location

Jan 12, 2024, 9:00 AM AST – Jan 14, 2024, 5:00 PM AST

Truro, 692 Prince St, Truro, NS B2N 1G6, Canada

About the event


The second part of the course will focus on the inter-relationship with cranial nerve V, VII, IX and X. Further we will dig more into neuro-immunology, especially how inflammation reaches and spreads inside the brain, leading to specific neurotransmitters imbalance and depletion along with excito-neurotoxicity. We will see how key neurohormones interfere with neurotransmission and body neuroimmune processes. We will review the applied osteopathic general and specifically orientated treatment to target the neuroendocrine-immune system and the ANS. We will introduce bioelectronic medicine as a tool that can be used as well in our patient management system. We will review the rationale behind the use of safe non-invasive vagus and trigeminal nerve stimulation and their effects of the sympatho-vagal balance as demonstrated by HRV analysis.

Heart rate variability analysis will be performed before and after treatment (osteopathy and electrical nerve stimulation.

At the end of the course Part 2, the participant will be able to:

  • Understand the essentials relationships with cranial nerve V, VII, IX and the Vagus nerve.
  • Understand the Blood-Brain-Barrier related to immunology.
  • Understand the role of the Glia in immune responses.
  • Understand the importance of Gateway reflexes in immunology.
  • Understand the role of the key neurohormones in immunology.
  • Review and process Heart Rate Variability analysis based on a 3-lead ECG.
  • Review and conduct a patient-centred osteopathic treatment to modify the sympatho-vagal balance.
  • Understand the principle of non-invasive vagus nerve stimulation and its effects on the sympatho-vagal balance through the modulation of the central autonomic network via specific modulation parameters.
  • Conduct an HRV analysis based on short-term ECG.
  • Decide what best treatment, based on patient symptomatology, detailed case history and any other valuable information (like paraclinical assessments), would be the most efficient, if rationale and safe treatment can be conducted.

Content Part 2:

•  Applied anatomy: cranial nerves V, VII et IX

•  Inflammation and the blood brain barrier

•  Glia: Immune role

•  The GATEWAY reflexes

•  Key neurohormones in immunology and neurotransmission

•  Scientific evidence and indications of non-invasive vagus and the trigeminal nerve stimulation (nVNS and nTNS)

•  Applied osteopathic treatment (continue from Part 1) and HRV analysis

•  Vagus nerve and trigeminal nerve stimulation: indications, contraindications, stimulation parameters

•  Vagus nerve and trigeminal nerve stimulation: exercises

•  HRV analysis exercises before and after stimulation

•  Treatment protocols for nVNS and nTNS: case review and exercise

•  Other natural means to stimulate the vagus and the trigeminal nerve

Who Should Attend This Course

Participants of Part 1 (Ed.1 or Ed.2)

The course will be given at Legge Clinic, in Truro, Nova Scotia.

CEUs EARNED: 21h-equivalent at the end of part 2 with a certificate issued at the end of the course.

Early birds enrolling up before Nov. 30th : use the coupon code: NEISX22d to get a 15% discount!

Note: language will be English with French translation if needed.

·  Cancellation deadline: 4 weeks before


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Mion, F., Pellissier, S., Garros, A., Damon, H., Roman, S., & Bonaz, B. (2020). Transcutaneous auricular vagus nerve stimulation for the treatment of irritable bowel syndrome: a pilot, open-label study. Bioelectronics in Medicine.doi:10.2217/bem-2020-0004

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Grolaux P.J.D. (2019). Transcutaneous Vagus Nerve Stimulation in Private Healthcare Center: A Small-Scale Investigation Targeting Anxiety, Irritable Bowel Syndrome and Chronic Pain. J Neurol Neuromed 4(5): 7-22

Pascal J.D. Grolaux. Effects of Chronic Non-Invasive Vagus Nerve Stimulation in an Asplenic Individual with Rheumatoid Arthritis: Report from an n-of-1 Study., 12 April 2022, PREPRINT (Version 1) available at Research Square []


  • NEIS_vagus-2

    Sale ends: Dec 31, 5:00 PM AST

    Part 2 of Integrative Approach Targeting the NEI System and the Vagus Nerve.

    Tax: +CA$97.50 HST+CA$18.69 service fee



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